Rams will be without Darrell Henderson Jr

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The news: The Rams did without RB Darrell Henderson Jr. on Tuesday.

What it means in fantasy: Henderson was the Rams’ leading rusher with 283 yards and three touchdowns on 70 attempts. He also had 102 reception yards at 17 receptions. The Rams’ running game has been an abomination so far in 2022, ranking 31st in the league at 76.1 yards per game. Los Angeles also ranks 28th in run block win rate. The Los Angeles offensive line had 10 different starting combinations in 10 games. Henderson has seen three of the last four games with fewer than six rushing attempts. Cam Akers and Kyren Williams will form a committee to move forward. Henderson’s departure benefits Akers the most. He had a team-high 14 rushing attempts and 61 yards against the Saints on Sunday. The Rams have a 3-7 record and are essentially eliminated from the playoffs.


The news: The Panthers named QB Sam Darnold the starter against the Broncos on Sunday.

What it means in fantasy: Darnold will be the Panthers’ third quarterback this season. He started in 11 games for Carolina last season after getting into a trade with the Jets. Darnold did not play this season due to an injury. It will be a great time for him to show what he can do as the season wraps up and he prepares for the free hand. On Sunday against the Ravens, Mayfield had a 20.4 overall quarterback rating, giving him a league-low 17.8. He had a 57.8% completion rate. Even with Darnold as quarterback, D’Onta Foreman and DJ Moore will be the Panthers’ most reliable fantasy starters. In 12 games with Darnold last season, DJ Moore caught 68 of 118 goals for 848 yards and three touchdowns.

go deeper: Darnold was 4-7 as a starter for the Panthers last season and had a 38.6 QBR, ahead of Zach Wilson (33.4) and Justin Fields (31.4).


The news: Broncos RB Chase Edmonds was placed on injured reserve.

What it means in fantasy: Since Sunday’s game against the Raiders, the Broncos have lost Edmonds to a high ankle sprain and are without Melvin Gordon III due to his fumbling ailments. Murray finished the game with 72 yards and a touchdown on 21 touches. He posted a season-high 17.2 fantasy points and can be considered an RB2 based on volume alone. Jerry Jeudy also did not train on Tuesday due to an ankle injury. He hasn’t played since he was taken away in week 10.


The news: The Cardinals have fired offensive line coach and run game coordinator Sean Kugler.

What it means in fantasy: Kugler has been on the Cardinals coaching staff since 2019. He designed Arizona’s running pattern, which has been struggling lately, failing to get 100 yards in three of its last four games. The change could result in significant changes that will benefit James Conner, who has scored 11 or more fantasy points in three straight games, including a season-high 23.6 points. The Cardinals are ranked 12th in run block win rate.


The news: Cardinals head coach Kliff Kingsbury said WR Greg Dortch will have a thumb MRI.

What it means in fantasy: Dortch played 91% of offensive snaps and ran the same number of routes as DeAndre Hopkins did Monday against the Cardinals after Rondale Moore’s groin injury on the first drive. Dortch rushed for a season-high 103 yards. Injuries are piling up for the Cardinals. Marquise Brown has been on injured reserve since suffering a foot injury in Week 6. He completed some individual exercises in training last Wednesday after being marked for the return. His week 12 status is uncertain. A hamstring injury has kept Kyler Murray out of the last two games. It’s possible Brown and Murray will miss another week with the Cardinals bye in Week 13. Arizona would be wise to lean on James Conner and the ongoing game against the Chargers in Week 12. The Los Angeles defense yields the third most fantasy points per game to running backs.


The news: Steelers head coach Mike Tomlin said RB Jaylen Warren was a doubt against the Colts on Monday with a hamstring injury.

What it means in fantasy: It’s not encouraging news for Warren this early in the week for a Monday night game. Najee Harris is well-positioned to see significant touches for a Steelers team that has one of the most favorable running back schedules for the remainder of the season. Harris had a season-high 24 touches and 27.6 fantasy points against the Bengals on Sunday. He has scored 10 or more fantasy points in four of his last five games.


Today on ESPN.com/Fantasy and on the ESPN Fantasy App

Field Yates Fantasy Field Pass: Latavius ​​Murray, George Pickens among aspiring fantasy helpers

Mike Clay’s Thanksgiving Playbook

Mike Clay’s Shadow Report: Analyzing matchups between wide receivers and defensive backs

Seth Walder’s next-gen stat advantage: Mismatches to exploit

Tristan H. Cockcroft’s positional matchup card

Matt Bowen’s Fantasy Movie Room: Gabe Davis, Alvin Kamara during week 12 upgrades, downgrades

Al Zeidenfeld’s DFS best buys for week 12

DFS cheat sheet for DraftKings and FanDuel

• Rankings for individual defensive player leagues

• Fantasy Focus Podcast (10:00 AM ET)

Thursday:

No daily Thanksgiving notes. We will track inactives before all three games.

In case you missed it:

• Week 12 fantasy football rankings at each position (PPR and NPPR)

Streaming pickups by Matt Bowen: deeper picks for lower leagues and emergencies

Eric Karabell’s Flex and Superflex Leaderboard for Week 12

• NFL Nation’s Fantasy Fallout: Beat Reporters answer our most pressing fantasy questions

• Eric Karabell’s trade index and rankings for the remainder of the season for week 12 and beyond

• Fantasy Focus Podcast: Field Yates, Daniel Dopp and Stephania Bell recap a big MNF win for Stephania’s 49ers before providing injury updates and talking about who needs to be in your lineup this Thanksgiving. Also, Eric Moody is joining the show to discuss the players you need to add for week 12. Listen | watch

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